human tim 3 fc Search Results


recombinant tim 3  (R&D Systems)
94
R&D Systems recombinant tim 3
Recombinant Tim 3, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant tim 3/product/R&D Systems
Average 94 stars, based on 1 article reviews
recombinant tim 3 - by Bioz Stars, 2026-04
94/100 stars
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wells  (R&D Systems)
93
R&D Systems wells
Wells, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/wells/product/R&D Systems
Average 93 stars, based on 1 article reviews
wells - by Bioz Stars, 2026-04
93/100 stars
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human tim 3 fc fusion protein  (BPS Bioscience)
86
BPS Bioscience human tim 3 fc fusion protein
Human <t>TIM-3</t> IgV domain binding with 10 mM Ca ++ by NMR. ( a ) Plot of peak shifts showing 15 N-HSQC combined chemical shift changes index, expressed as [(ΔHcs/0.1 ppm) 2 + (ΔNcs/0.5 ppm) 2 ] 1/2 ,of hTIM-3 IgV upon binding with 10 mM Ca ++ . The data columns are colored according to degree of index changes (red > 1.0; green > 0.5; yellow > 0.25). The chemical shift change indices of Met118, Asn119 and Glu121 in F-G loop of hTIM-3 exceeded 2.0, even at well below the saturation concentration of Ca ++ binding. ( b ) Chemical shift changes of hTIM-3 backbone amides induced by 10 mM Ca ++ binding, mapped on to hTIM-3 crystal structure surface and colored by degree of index changes as in ( a ). The opposite BED and AGFCC′C″ faces are shown in the left and right panels, respectively, with the B-C, C-C′ and F-G loops marked in italics.
Human Tim 3 Fc Fusion Protein, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human tim 3 fc fusion protein/product/BPS Bioscience
Average 86 stars, based on 1 article reviews
human tim 3 fc fusion protein - by Bioz Stars, 2026-04
86/100 stars
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human tim-3 / havcr2 recombinant protein mouse igg fc tag lyophilized  (Innovative Research Inc)
N/A
Human TIM-3 / HAVCR2 Recombinant Protein Mouse IgG Fc Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in Tris with Glycine, Arginine and NaCl, pH7.5
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recombinant human tim 3 fc chimera protein cf  (R&D Systems)
N/A
The Recombinant Human TIM 3 Fc Chimera Protein from R D Systems is derived from NS0 The Recombinant Human TIM 3 Fc Chimera Protein has been validated for the following applications Binding Activity
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human tim-3 recombinant protein fc igg1 tag lyophilized  (Innovative Research Inc)
N/A
Human Tim-3 Recombinant Protein Fc IgG1 Tag Lyophilized from Innovative Research has been recombinantly produced in CHO cells. This is a Lyophilized protein buffered in Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 and#956;l
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human tim 3 protein fc avi tag biotinylated  (Sino Biological)
N/A
A DNA sequence encoding the human HAVCR2 NP 116171 3 Met1 Arg200 was expressed with a c terminal AVI tagged Fc region of human IgG1 at the C terminus Fc AVI The expressed protein was
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tim 3 mouse fc fusion human avi tag hip  (BPS Bioscience)
N/A
Mouse TIM 3 also known as T cell immunoglobulin mucin receptor 3 T cell membrane protein 3 TIMD 3 Hepatitis A virus cellular receptor 2 HAVCR 2 and KIM 3 GenBank Accession No NM 032782
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human tim-3 recombinant protein c-fc-6 his tag lyophilized  (Innovative Research Inc)
N/A
Human TIM-3 Recombinant Protein C-Fc-6 His Tag Lyophilized from Innovative Research has been recombinantly produced in Human Cells. This is a Lyophilized protein buffered in Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. It
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human tim-3 recombinant protein fc igg2a tag lyophilized  (Innovative Research Inc)
N/A
Human Tim-3 Recombinant Protein Fc IgG2a Tag Lyophilized from Innovative Research has been recombinantly produced in CHO cells. This is a Lyophilized protein buffered in Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 and#956;l
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recombinant human tim 3 fc chimera carrier free  (BioLegend)
N/A
Recombinant Human TIM 3 Fc Chimera carrier free Apps BA Size 10 μg
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tim 3 mouse fc fusion human avi tag biotin labeled hip  (BPS Bioscience)
N/A
Mouse TIM 3 also known as T cell immunoglobulin mucin receptor 3 T cell membrane protein 3 TIMD 3 Hepatitis A virus cellular receptor 2 HAVCR 2 and KIM 3 GenBank Accession No NM 032782
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Image Search Results


Human TIM-3 IgV domain binding with 10 mM Ca ++ by NMR. ( a ) Plot of peak shifts showing 15 N-HSQC combined chemical shift changes index, expressed as [(ΔHcs/0.1 ppm) 2 + (ΔNcs/0.5 ppm) 2 ] 1/2 ,of hTIM-3 IgV upon binding with 10 mM Ca ++ . The data columns are colored according to degree of index changes (red > 1.0; green > 0.5; yellow > 0.25). The chemical shift change indices of Met118, Asn119 and Glu121 in F-G loop of hTIM-3 exceeded 2.0, even at well below the saturation concentration of Ca ++ binding. ( b ) Chemical shift changes of hTIM-3 backbone amides induced by 10 mM Ca ++ binding, mapped on to hTIM-3 crystal structure surface and colored by degree of index changes as in ( a ). The opposite BED and AGFCC′C″ faces are shown in the left and right panels, respectively, with the B-C, C-C′ and F-G loops marked in italics.

Journal: Scientific Reports

Article Title: High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3

doi: 10.1038/s41598-018-35754-0

Figure Lengend Snippet: Human TIM-3 IgV domain binding with 10 mM Ca ++ by NMR. ( a ) Plot of peak shifts showing 15 N-HSQC combined chemical shift changes index, expressed as [(ΔHcs/0.1 ppm) 2 + (ΔNcs/0.5 ppm) 2 ] 1/2 ,of hTIM-3 IgV upon binding with 10 mM Ca ++ . The data columns are colored according to degree of index changes (red > 1.0; green > 0.5; yellow > 0.25). The chemical shift change indices of Met118, Asn119 and Glu121 in F-G loop of hTIM-3 exceeded 2.0, even at well below the saturation concentration of Ca ++ binding. ( b ) Chemical shift changes of hTIM-3 backbone amides induced by 10 mM Ca ++ binding, mapped on to hTIM-3 crystal structure surface and colored by degree of index changes as in ( a ). The opposite BED and AGFCC′C″ faces are shown in the left and right panels, respectively, with the B-C, C-C′ and F-G loops marked in italics.

Article Snippet: For binding studies between human TIM-3 Fc fusion protein (BPS Bioscience) and tagless hCEACAM1 IgV domain, 50 μl of 250 nM tagless hCEACAM1 protein in Tris-buffered saline buffer containing 10 mM CaCl 2 (TBS-Ca ++ ) or TBS-Ca ++ buffer alone was added to wells of an ELISA plate and incubated overnight at 4 °C.

Techniques: Binding Assay, Concentration Assay

Human TIM-3 and human CEACAM1 binding studies by ELISA. ( a ) hTIM-3 Fc fusion protein but not hIgG-Fc fusion protein (0–4 μM) binds to tagless hCEACAM1 IgV domain with EC 50 of 1.50 μM. ( b ) Blockade of the interaction between tagless hCEACAM1 and hTIM-3 Fc fusion protein with 10 μM of hTIM-3 C-C′ loop-derived peptide (amino acids 58–77) but not by 10 μM of scrambled peptide. ( c ) Binding of tagless hTIM-3 IgV domain with glutathione-S-transferase (GST) tagged hCEACAM1 IgV-domain protein (0–15 μM) with EC 50 of 3.13 μM, but not with GST protein (0–15 μM). ( d ) Significant blockade of interaction between tagless hTIM-3 IgV domain and glutathione-S-transferase (GST) tagged hCEACAM1 IgV-domain fusion protein by a mouse anti-human CEACAM1 IgV-domain specific monoclonal 5F4 antibody (0–1 μM), but not by a isotype control MOPC antibody. ( a–d ) ELISA binding assays were performed in triplicate and the average values are shown with standard deviations. n.s., not significant. p values ≤ *0.05, **0.01, and ***0.001.

Journal: Scientific Reports

Article Title: High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3

doi: 10.1038/s41598-018-35754-0

Figure Lengend Snippet: Human TIM-3 and human CEACAM1 binding studies by ELISA. ( a ) hTIM-3 Fc fusion protein but not hIgG-Fc fusion protein (0–4 μM) binds to tagless hCEACAM1 IgV domain with EC 50 of 1.50 μM. ( b ) Blockade of the interaction between tagless hCEACAM1 and hTIM-3 Fc fusion protein with 10 μM of hTIM-3 C-C′ loop-derived peptide (amino acids 58–77) but not by 10 μM of scrambled peptide. ( c ) Binding of tagless hTIM-3 IgV domain with glutathione-S-transferase (GST) tagged hCEACAM1 IgV-domain protein (0–15 μM) with EC 50 of 3.13 μM, but not with GST protein (0–15 μM). ( d ) Significant blockade of interaction between tagless hTIM-3 IgV domain and glutathione-S-transferase (GST) tagged hCEACAM1 IgV-domain fusion protein by a mouse anti-human CEACAM1 IgV-domain specific monoclonal 5F4 antibody (0–1 μM), but not by a isotype control MOPC antibody. ( a–d ) ELISA binding assays were performed in triplicate and the average values are shown with standard deviations. n.s., not significant. p values ≤ *0.05, **0.01, and ***0.001.

Article Snippet: For binding studies between human TIM-3 Fc fusion protein (BPS Bioscience) and tagless hCEACAM1 IgV domain, 50 μl of 250 nM tagless hCEACAM1 protein in Tris-buffered saline buffer containing 10 mM CaCl 2 (TBS-Ca ++ ) or TBS-Ca ++ buffer alone was added to wells of an ELISA plate and incubated overnight at 4 °C.

Techniques: Binding Assay, Enzyme-linked Immunosorbent Assay, Derivative Assay